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Dutasteride: Drug Information
Dutasteride is a medication that is used in men for the treatment of urinary problems due to benign prostatic hyperplasia. This condition is commonly referred to as enlarged prostate. As the prostate enlarges, it often causes problems with urinating. Use Dutasteride if you experience the following symptoms of prostate enlargement:
Weak urine stream
Difficulty emptying bladder
Difficulty starting urination
Excessive urination at night (nocturia)
Dutasteride can be used in combination with tamsulosin, which is another medication for BPH.
Taking Dutasteride also reduces the chance of needing surgery to treat benign prostatic hyperplasia. Off-label uses of Dutasteride include the treatment of male pattern baldness and prostate cancer following the prostatectomy.
Dutasteride: Mechanism of action
The symptoms of benign prostatic hyperplasia are caused by the male hormone dihydrotestosterone. Dutasteride contains the active component dutasteride. Dutasteride blocks the conversion of testosterone into dihydrotestosterone, thereby reducing DHT levels in the body and shrinking the enlarged prostate. Therefore, dutasteride helps reduce enlarged prostate symptoms.
Dosage and Administration
Swallow Dutasteride capsules whole without crushing or breaking them. If you crush the capsule before swallowing it, the medication can irritate your mouth or throat.
The only one recommended dose of Dutasteride for the treatment of benign prostate hyperplasia is 0.5 mg taken once a day. Do not adjust your dose unless it was your doctor who has instructed you to do so. It is important to take Dutasteride regularly to get the most out of treatment.
It may take three months to one year for Dutasteride to take effect and improve your symptoms. The effect of Dutasteride lasts as long as you take the medicine. If you discontinue the medication, the prostate begins to enlarge again.
It is important to maintain an even level of dutasteride in the blood, so you should take Dutasteride at the same time.
You will find more information on when and how Dutasteride should be taken in the Patient Information Leaflet. Read this information carefully before you use Dutasteride.
Dutasteride: Important safety information
Among the medical conditions you should tell your doctor about before using Dutasteride are liver failure, liver disease, or any allergies.
Tell your doctor about all of prescription and non-prescription medications you’re taking prior to using dutasteride to reduce the risk of drug interaction.
Dutasteride should not be given to pregnant women. For that reason, you should not donate blood for six month after you discontinue Dutasteride and while you are taking this medication. This will prevent the medication from being given to a pregnant woman.
Dutasteride is not for use by children and women. Since the medication can be absorbed to the blood through the skin, children and women should not touch Dutasteride capsules.
You should not take Dutasteride if you are allergic to dutasteride or any inactive ingredient of the medication.
Dutasteride may increase the risk of prostate cancer. Before using the medication, you and your doctor should weight the risks of taking Dutasteride against its health benefits.
Get medical help if you develop any symptoms of an allergic reaction, including difficulty breathing, rash, itching, or swelling.
Read Patient Information Leaflet carefully before you use dutasteride to make sure that Dutasteride will not cause harmful effect.
Dutasteride: How Supplied
Propecia comes in a capsule form and is available in a 0,5 mg strength.
Dutasteride: Side effects
If you are going to use dutasteride, be aware of possible side effects that this medication may cause:
Decreased sexual ability
Less common side effects may include fatigue, chest pain, breathlessness, and irregular heartbeat. However, these side effects are usually mild and rare, and most patients tolerate Dutasteride well.
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